Substrate Anchoring and Flexibility Reduction in CYP153AM.aq Leads to Highly Improved Efficiency toward Octanoic Acid
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چکیده
منابع مشابه
Improved amino acid flexibility parameters.
Protein molecules exhibit varying degrees of flexibility throughout their three-dimensional structures, with some segments showing little mobility while others may be so disordered as to be unresolvable by techniques such as X-ray crystallography. Atomic displacement parameters, or B-factors, from X-ray crystallographic studies give an experimentally determined indication of the degree of mobil...
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This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed, or repre...
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The regulation of ketogenesis in the rat has been studied both in uiuo and in the isolated perfused liver with octanoic acid as substrate. This fatty acid, which is not utilized directly for triglyceride synthesis, was chosen in order to investigate the events that govern the metabolism of fatty acids subsequent to the (?-oxidation process. Experiments in viuo established that for any given loa...
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ژورنال
عنوان ژورنال: ACS Catalysis
سال: 2021
ISSN: 2155-5435,2155-5435
DOI: 10.1021/acscatal.0c05193